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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce90350b07b54801b01f7766ea9e1e51376e8e94ce7c3085dd50b2c3a2d12885' 
  AND token = 'Mc8Ne8ob08QsrDkDJQLyU56XLOYTv8rGrY/YBRC2c7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}