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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de911c7c7c09caac4c3bb62c4d586f9d1aa4515eedeb9d85ef9d1dce19fbf16' 
  AND token = 'JCdqzgV+vYXiqrCU0H44n0SVFIPTRIKs3iQiCg5TZnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}