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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177faa4cfa671743a5685082ee7d8a3e9481c5c90100362c8e91871a6dec0d31' 
  AND token = '+DcRgz1zGUmh2Xac5gawx26gVgVz6oRYbF7vTzvJ1Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}