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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26225da55dadb0800fbcf3274104679cf99bc09544eacee2e65c8e9cdbbe6994' 
  AND token = 'q+MFE3vc/BlzcoHW6SA61G8uQbzi8HV1x6nPzsg3iRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}