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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a906f452400ddd78057c6f085b2bef8e39a825f567e7856be9e642bda788b19c' 
  AND token = 'tp9hoTVDpqQhQTP1B7i2nqOPR0CinYryRmAS740INwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}