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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5117907145ab5747c8af69117fe6ea89bdbb204b95caafc8c565314b6f3a8c3c' 
  AND token = 'vMug65A6djHRBrsxd2peWbGBtxABhOeAJe0UqWwGN30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}