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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a822f85be6cb6ec1621831bc5235120c1730d7a6cc00dba72c4ecb4c3a284f' 
  AND token = 'TvQqvgBWZCAp3Zbjj+rE45CXGJuM8Hok82VwnM0OZEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}