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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c16b48d2de7d9f7d5866a2b92511711742683e6197c0b9dccc6ec4317829b0' 
  AND token = 'QzX01u1fhpdEF+Z6cT69zhF5oCbZ6nRRqfo6UzuwFa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}