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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91c4580cb37cd343b6280d0df2c138e3751244169c0f652df2a8a23105385af5' 
  AND token = '0L3sDiEdky+8V+HIQUx9+rs/HUCZ9Jprv4kzBLwfSLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}