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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1edd8e7505d39bd1c5a8a6b0951b7035222fce3f92c28302072abb7b544a53b7' 
  AND token = 'PKw+iUEMETqXC0nXOp6zr2FGiGxpk13O0UXFm0aEzZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}