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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb156fea31c1e1e7a820868bcffed73485ad721c27593ad0bc8e42ece4ec971' 
  AND token = 'BbR0an+tqL9vmSrfRihxoBtYNSAZuH9aGbLfZKcnzqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}