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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5fa71bceb948c4e04da852bd6227c7bd1f1404002416122ebbf0df0244fc575' 
  AND token = 'nOiRpfnBcKewB2dO3OMKznEcDB1uvZteO2+ihx8+XHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}