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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aca5e4155656e358face37c1fa77f4c80e533d032ee8fccc4aab1af63a412d0' 
  AND token = 'syqRf7H1v5OzKfCLYZgALxHH226OHtwn0Safk7pTEeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}