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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf80df1b4314a0311cfe416de89c305a5b53a322ea04f0689f07ff1099b2613' 
  AND token = 'WkkXdhhPZAhmkZZd7mu8CfIEt92WpfE6ap/1KGHSnG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}