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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02142881d81a42e5a9ebd55cdb926bf438c4dcfdf15fa06c92ba061ab42490a1' 
  AND token = '99COKiRV+52hSla6720h3utNGI1mDQWSQTGsjXw6E9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}