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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b339d0fecd247738e1f3df2d25088fd8b111fdd8766d35c898794c210a088b' 
  AND token = 'fwDbV6liTm9dRkRgOORvmcdEySotxqKCpd3nUeBS1EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}