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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f406c46d3650088f1892fbdbbafaf7e14c9f19ac040491c828cee535615137' 
  AND token = 'cnv+Z/PsIodm9J3toVPE0y+dwPbE1+P+5TQ7xPMiNlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}