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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08cb45c35c7be32905f8c8771bc32174ac362b296900b3d118b72c2209d8fce3' 
  AND token = 'IbETXeMzLNu8AcmN/fj2TITa8HObunbOfV47XRnCdZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}