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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45a10d8e032337218d687e799bd0e1dd1e553577fb3e84b2806a4c46931095a' 
  AND token = 'mN/xR31yzh5bwu+8zcmcmkl7IKRM2nZ4/I1uU/t07hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}