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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05272f289d23f8e8234574887ccdfd0cc97cac5e6492d4be6b52d687d7c5d2b8' 
  AND token = 'v2a+WNrOmFDGxTVWo6KSstBqGlEDlpUBVnaPDEqs+Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}