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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d969e4c4bbce1c94567460710c3866b2a68aa8e492b879fa6511030f7013e36' 
  AND token = 'n+GD23D2K/qxc457b+9DKBCNNPjHA8uJBBD9CzqF/ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}