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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacba78e6519314c88f9f3e1447f9799752b0df24b3968508e5fc7f7e64c978a' 
  AND token = 'M0UAeWswMTceF5H+1+AuQN/uzFkqhRerIFF+2VJiSEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}