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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b5572e45b2973e7fa6df71736afd9e9fa9cba13b0ccd9ed97328bc3191026a' 
  AND token = 'YQ5pR4n0LOjc0RSRsLUFC5K2sE004LJ8w5LpUvzrC+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}