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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f111ecbde65c9011dba6316b1da14ef26a6213155ccd654b4912fdcf60536c3c' 
  AND token = 'YlpjoSWs4cHKbxU+pzTve0cLN/nmlqIPuIFehzpvtLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}