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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8295032143c89d3a4710caf8baf7f0ce18f0969b1255cf0eb77de3591b5535e3' 
  AND token = '7pFIpzREIST74yf+0NeZEioZwZ+KPnwHfeYYBJtcxJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}