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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd293c35dc7287214d1ffb5072d76c34d74a3fa274ad16ab2e1cf7c261c28abd1' 
  AND token = 'V8buk5mpwf5PTSYTB2sv1NwkfMnYd2lMtvIriEic8b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}