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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9953bbb6518e0aafa30601123f8b6ee71fd3a9f57ef7485f2cb4744e5136da1a' 
  AND token = 'EzuX2PyH2MDU+xDY/JRgNWTsoQWKJn4VJQbyRuA/2Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}