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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c3058ce83c679e390f020d655d2dc2a1b71b57a05ef8f3ea7fd22a5a713a97' 
  AND token = 'oHC1dd2+ao3Lom7b1rKGvtBQlXLbz853dLRl1w4uZ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}