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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720efadb14d8c0ebdffa0f7fb9a603291d1184929d2fde39207f0e021370b1f3' 
  AND token = 'Eb5JRuvj9pA7f1o6XlvLoFRRF+QVLun9oElFieDerDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}