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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54cd48f6dec59c26d72bdb87587943bdae25c9f8df8472a6e799246d98403687' 
  AND token = '7AxAX2a2/w9BLyIo2CMd7WCyrxOsAgYiq2MnLPzMo44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}