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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e9b0d66038d09154edb8d3382c572de9d0a005ccddc8c6fb023271687838b8' 
  AND token = 'kdBXQS32d6/Qvmdc86Y9lJEDykovte7C5KQ7+rma9Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}