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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d818e50145379ec78206bc888061b54ef949c85aa204feefb1f5da05a53e7c' 
  AND token = 'JhnuEFsXd6Qwg/qJGj4wg5yA6WmU1625Ine/mOGWR8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}