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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9e82954335e4e3195842ff217b1c2f50c1e358b38e4bbf6a882071bce9cb6d' 
  AND token = 'FaR4N6WoRyy24ykW3WWx+vu/b8j2pv4ocp4lAUvpY38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}