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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482021698ebdefa7ea366e41e82571238f795a18fd25c43f8988c4a01cf4e7c0' 
  AND token = '1u3ozZu6V3ZGwSzxZYnnga09bvWAnX44cNATAyr+E7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}