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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4f31a286f344ad681b2cf456e1dd345c31e4964140b2047034bc68194da56a' 
  AND token = 'S4jxRmEIYJt8fhtq3+M76YvVZdRtWxdBI5po3g/yJ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}