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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eff64a060a4b0d8cd364931919d2d49d3e96770749ef4a3870f653cf4c1e9b0' 
  AND token = 'GcTKYFOQE3CzaC5N8RUfOVlnI0yWLGe1G0WgpyOcad0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}