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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8246e6c95de4d16d4348c7c726f8e24971c57fa4beb989046d48700e3ddfe90' 
  AND token = 'Zsh06SRojfdxEusRkHLsZZL63JA5fS4crqPd69AJAAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}