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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9913e5dd2eeafc972aaccb938ea869f3ac1656ac3664b74dbf4fbf1eb4dd6f71' 
  AND token = 'BFbRtaWqxpPVfkLOSjy8ns1z5C8sbZmY05lPOAxM61c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}