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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17324abd50867726a06652b6c21f403bde03228089ce2c308b2fe7114bdc346a' 
  AND token = 'QAbWAdUuqkLhsgbWRQtcjH+wGUJQaFcJk6sp/1ZXy7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}