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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc2058f672bddd7a181b2e33752ea8362eb38409796b75a3c50e80042d862f7' 
  AND token = 'DQO9d8BNEWriNEoThpKzkC4nBYrDvMupPW9xpgPsUAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}