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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b146f4b72ef7446d16a4f7709a2ea6d556137a26a4034a85de5f415aadabc9c8' 
  AND token = 'P5bQiHd+TZ8CEYE1IwjncUmG/9aUsiPg/0+lOFuzs0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}