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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399be32684330e0a28fcb95511408578e4c923364cabc3a0537487b7cd9b1343' 
  AND token = 'gDFhzq7zUDgSIdRzHuNDAi2v3tX7trI6SZ96pUW7XTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}