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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef55bbcb2e14de97821bc9a5eb902cbbf9605f43475e682344206b5d69bd315' 
  AND token = 'z3kf12G9OmYKRlyIjcpAHf1W/IS8HwGLap1wPDFMt58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}