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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2020d3fdc62f68bb50a0b80939618cd6a9f098b1da52bb1175208677919e3686' 
  AND token = 'rD+m7MVu7T8g0g2vgJ+FjHcwNNpstj/DkON++c8/XGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}