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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f3f3b40c13a9d4741241c68caf9805e06296adeb59e2582923b1263b4a815c' 
  AND token = '9YBSFgEs4QOqhP0nYHOkIEGP2lD5N6NU3CwvkHHdA8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}