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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c0869a9eed3e9536e1e0a11e6aa06b392a936e976f0c672e2b929176f88330' 
  AND token = 'DfViZ9bWM1M+5kEp4H+Fz9t69HnN1khAsXt3pgHM2IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}