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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0cb1c866250a62987844c6c6cc01982b4249b50011cd53203f7d14bbcd69dad' 
  AND token = 'v4qU02rG4XD3BuoIflUh7md5Wm4MCeELkcOZT4DFmRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}