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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485d65504c04da5884d20eadf00d68bb7fa8d073d7d86e8f3887b09d33ce4061' 
  AND token = 'H1thd8KshPKXVBwlbZvAbuMiJOMVQVXalrwZyq3i/FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}