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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7163e27c4819837144265e63470762da0d4deb1aa5a7f31d6ab04b259e7f66' 
  AND token = 'HhQ5Jhw64AmpdT+3kl3eyGaB2bf5UTQ7sI8FutApe1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}