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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd16d58889396b22d21b0ac341be4b0a4d0e22eb6a6020242bf8e208bc0df3b' 
  AND token = 'Tb2MgaTQKcuBarh6DE+AiWazOWbJvCT98QonenF8Afc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}